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Niraj Satnalika wrote on 30 Dec, 2012

Limited Liability Company is a hybrid business entity having some features of a corporation, a partnership or sole proprietorship business. It is more of an association than a corporation. It is seen that many people choose the Limited Liability Company as their form of business, mainly because of the ease in set up and operation. It is more preferable for a single owner.

Main Difference from other forms of Business

The main difference of a Limited Liability Company, from other forms of Business are:

i) The only point an LLC differs from Sole proprietorship is that in case of an LLC, the owners are not open to personal liability.

ii) LLC differs from Partnership with the fact that it does not subject the owners to the consequences of bad legal or financial decisions by one partner.

iii) LLC differs from a Corporation where it does not have double taxation on profits.

Advantages of Limited Liability Company

Some of the advantages of starting an LLC are as follows:

Limited Liability Companies, much like corporation, provide protection for their owners. If the organization has debts that it cannot pay, the individual owners will not be held responsible for those debts. If the organization has to file bankruptcy the individual owners are still not personally responsible for any of the liabilities that the organization has.
Owners can choose to have profits distributed anyway they would like. This means, whatever percentage of profits they want to give to each member, they have the flexibility to do so.
Reduction in paperwork, tedious meetings and note-taking that are required by corporate entities are not required by an LLC. There are no board meetings or quarterly meetings required. There are no quarterly or semi-annual reports that are necessary for the IRS.
There is no double taxation. There is no need to pay taxes on corporate profits, as well as on profits that pass to members. You only pay taxes once, and that is on those profits that are given to individual members.

Disadvantages of Limited Liability Company

Following are the disadvantages of starting a Limited Liability Company:

Longevity of the company is based on the life of the members. The company will dissolve if a member goes bankrupt or passes away.
?This is not the best form of business to set up, if you are planning on distributing shares later to shareholders. It is not the best business entity to set up if you are planning on going public.
New challenges may be encountered, in terms of the way that the organization files taxes. The LLC can be designated as other kinds of business entities when it comes to completing tax returns, such as, a corporation, partnership or sole proprietorship. Of course selecting the sole proprietorship format would be the easiest to complete, but you may not have a choice. This status may be automatically selected for you. Check with your tax advisor to be sure.

Examples of Limited Liability Company

Some of the examples of Limited Liability Company are as follows:

Chrysler Group, LLC
Westinghouse Electric Company, LLC
Dougherty & Company, LLC

Read more about Advantages & Disadvantages of

i) Sole Proprietorship Business

ii) Partnership Firm

iii) Corporation.

?

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Niraj Satnalika

Niraj is an Engineer and currently pursuing an MBA in International Business (Finance) from IMT Ghaziabad. He is actively involved with an NGO working for the promotion of education among the underprivileged

Source: http://www.greenworldinvestor.com/2012/12/30/advantages-and-disadvantages-of-a-limited-liability-company-llc/

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The Samsung Galaxy S3 Mini will not be involved in the next round of the never-ending Apple vs Samsung patent war.

The little brother of the flagship Galaxy S3 had been named alongside a host of Samsung devices which, according to Cupertino, infringe Apple's intellectual property.

The warring companies had been asked to present their lists of disputed devices as they gear up for a second trial in California, scheduled to begin in March 2014.

As the Galaxy S3 Mini is not being sold in the United States, Apple has sportingly agreed to strike it from the list.

Round two

However, it's not as if Samsung will be doing cartwheels about the news. Apple's list still includes the Galaxy S3, Galaxy Note 2, Galaxy Tab 8.9, Galaxy Tab 2 10.1 and Rugby Pro devices.

Apple also reserves the right to reinsert the S3 Mini if Samsung decides to launch it Stateside.

The second trial, which follows Apple's crushing victory this summer, will also hear Samsung's claims about the iPhone 5.

Via Apple Insider

Source: http://rss.feedsportal.com/c/669/f/415074/s/270e1e46/l/0L0Stechradar0N0Cus0Cnews0Cphone0Eand0Ecommunications0Cmobile0Ephones0Capple0Edrops0Epatent0Eclaim0Eagainst0Esamsung0Egalaxy0Es30Emini0E11218590Dsrc0Frss0Gattr0Fall/story01.htm

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Source: http://www.medicalguide.pro/3868/simple-abundance-exercises-can-change-your-mindset-8.html

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Sorry, Readability was unable to parse this page for content.

Source: http://www.mistagreenproductions.com/archives/733

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Sorry, Readability was unable to parse this page for content.

Source: http://mimshah.blogspot.com/2012/12/self-improvement-times-time-management.html

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UFC 155 is only a day away. It's time for picks from Yahoo! Sports' columnist Kevin Iole, Cagewriter editor Maggie Hendricks, and Cagereaders who posted their picks on Facebook.

Kevin Iole: Junior dos Santos W5 Cain Velasquez -- I can't believe I'm picking against Velasquez. To me, he is in many ways the perfect heavyweight, with great conditioning, great wrestling and tremendous power. But how do we ignore what dos Santos has done? Much was made of Velasquez's knee injury before their first fight, but what isn't as well known is that Junior had a bad leg, too, and couldn't do much. It's going to be a dogfight, but I think Junior finds a way to pull it out.

Maggie Hendricks: Cain Velasquez W5 Junior dos Santos -- Velasquez was injured in his last bout with JDS. With a healthy knee, he'll get to use his wrestling to control and beat on JDS for five rounds.

Cagereaders: Couldn't ask for a better way to end the year than this rematch. This will last longer than the first but not by much. I'm picking Cigano by KO R1. Cain has amazing wrestling and ground and pound. However, I think Junior is the guy that has his number and things won't go as planned for Cain. Velasquez will come out more aggressive than the first fight and that will spell the end. Junior will rock him with some brutal counters causing Cain to shoot in for the take down. Junior will stuff the attempt and finish the fight with an uppercut around 3 minutes into the first. -- Jackson Torres

[Related: Five questions that will be answered at UFC 155]
__

Kevin Iole: Joe Lauzon W3 Jim Miller -- Definitely will be the Fight of the Night in my opinion (is there any other kind of fight for Lauzon?) I don't think Joe will be able to submit Jim, but he is so active and works so hard I think he'll pile up the points to win.

Maggie Hendricks: Joe Lauzon Sub2 Jim Miller -- Lauzon's submission game is tough to beat. He will need to avoid Miller's well-rounded game, but can do it.

Cagereaders: My two favorite 155 pound fighters. When I saw Miller step in for Maynard, my heart sank. I'm going to see one them lose, and it looks to be J-Lau. Miller matches up really well for Lauzon's style. He has power in his punches and solid wrestling, backed up with a serious ground game and outstanding cardio. Joe has a killer instinct and a more dangerous ground game. Still, I like Miller taking this fought by a UD. -- Tom Hogan

--

Kevin Iole: Tim Boetsch W3 Costas Philippou -- Boetsch will grind out a victory by controlling the distance and limiting Philippou's power

Maggie Hendricks: Tim Boetsch W3 Costa Phillippou -- Ditto on what Kevin said. Boetsch won't make it a thrilling fight, but it will be a convincing win.

Cagereaders: Boetsch over Phillipou by 3rd Round TKO -- I think this fight will be back to forth, I have counted out Tim Boetsch in many fights just to be shocked, from the poor decision in the Lombard fight, to the amazing knock out of Okami, I think Phillipou gets the better of him early in the fight, while Boetsch owns the latter part of the fight, this could easily be fight of the night and if it does go decision, it will be close, but I see Phillipou gassing late and Boetsch taking advantage. -- Daniel Ryan

--

Kevin Iole: Alan Belcher TKO2 Yushin Okami -- This outcome would have been unthinkable a year ago, but Belcher improves tremendously each time out and is now one of the world's most complete fighters.

Maggie Hendricks: Alan Belcher W3 Yushin Okami -- With title shot hopes hanging over him, Belcher has good reason to fight a smart game and come out with a win over Okami.

Cagereaders: Yushin Okami will beat Alan Belcher by decision. Okami will go back to what made him successful before his fight with Anderson Silva. He will use his jab and height, keeping Belcher back, then take him down for ground and pound. This will continue for 3 full rounds and Okami will come out with the unanimous decision. -- Marcus Min

__

Kevin Iole: Chris Leben TKO3 Derek Brunson -- This is a big fight for Leben, and I think he knows it. I expect him to eventually catch Brunson with something big that will end it.

Maggie Hendricks: Derek Brunson W3 Chris Leben -- In his first fight after a long layoff, Leben will have a hard time dealing with a wrestler with power like Brunson.

Cagereaders: Derek Brunson should be able to defeat Chris Leben by decision because he has a great wrestling background and Chris Leben may not be in the best shape coming off a 13-month layoff. -- Edgar Diaz

Related MMA video from Yahoo! Sports

Other popular content on the Yahoo! network:
? Junior dos Santos has something to prove vs. Cain Velasquez
? Dana White's refreshingly honest take on drug use in UFC
? Y! Screen: Hornets rookies discuss the facts of life in comedy clip

Source: http://sports.yahoo.com/blogs/mma-cagewriter/ufc-155-picks-kevin-iole-maggie-hendricks-cagereaders-161442619--mma.html

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Sofia Vergara shares a bikini photo from her vacation! Plus, check out more stars' cute, candid and crazy Twitter photos

Source: http://www.ivillage.com/celebrity-twitter-pictures/1-b-229669?dst=iv%3AiVillage%3Acelebrity-twitter-pictures-229669

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28 Dec 2012

Many individuals might have thought that beginning an online business is really a tough process. By now, you?d know about the truth that building an internet business is too hard than simply starting it. It could bring you lost of gains once you understand the key behind it, although it?s tough to construct an business. Effective online business people do not do any big things, they just do all the little things right. If you care for the basic principles and offer good, you too are certainly along the way to success. A few things that you simply require concentrate are outlined below.Niche: Pick the niche of your choice; do not remain beneath the influence of somebody else. The niche you choose should really be of maximum interest to you. your market needs to have less quantity of competitors. In case you have too many competitors, your business strategy should be able to outweigh the competitors. As soon as you stick to a site, it?ll be very difficult to improve reasons. Even though you opt to change, lots of time and energy gets wasted.Content: The material of your site by which you connect to the consumers must be breathtaking. Avoid unprofessional false and information data. Genuinely let them know that which you ?ve got and at once, glorify your item in the right way. This is your best possiblity to really build up a relationship with the clients. It?s a big stage in making an business.Outsource: If you feel you can not adjustable process, i.e., handle both the internet site and the inner content, outsource the content job to somebody else who could do it for you. While making a choice on outsourcing, pick the appropriate person and then spend rather than putting your cash on fillers.Promote: Promotion is critical to deliver a type of knock out punch in the conscience of the consumers. Selling involves critiques from a person who had previously used the item or required in your business, video presentations of the products and services, relationship with the men behind most of the business methods etc. Program accordingly on marketing your product and building an internet business. After than the product these days.Think Innovative: Building an internet business needs lot of execution and creative thinking all, the marketing is more significant. You can not only damage with common methods and techniques. You need certainly to show up with something new every single time you reach the customers. Variety in the technique and presentation fetches more customers. Nearly all the rivals might have similar ideas, with little differences there and here. You ought to money in on those few negatives and present your product while the final choice.Indeed, Building an internet business requires lot of execution, planning and thinking. The rewards are equally high. An intelligent strategy may make all of the difference for you.

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Source: http://katalogas.link-bin.eu/building-an-internet-business-steps-to-follow-to-help-you-earn-money-online/

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By Gael Fashingbauer Cooper, NBC News

Think you opened all your holiday cards this year? Here's another -- from Iron Man, or at least the superhero Avenger's real identity, billionaire Tony Stark.

@Iron_Man / Twitter

The card, showing Stark (Robert Downey Jr., in the role he was born to play) standing out in a snowy field, possibly about to catch snowflakes on his tongue, was tweeted out the day after Christmas from the official account set up for Stark.

Movie blog Cinema Blend points out that "Iron Man 3" writer/director Shane Black seems to love Christmas themes. Four of his screenplays, including "Lethal Weapon," were set during that holiday season, and "Iron Man 3" footage shown at Comic Con shows Stark enjoying Run DMC's 1987 single "Christmas in Hollis."

Stark isn't wearing his armor in the snowy shot because, according to the trailer, it's become non-functional.

"Iron Man 3" opens May 3, and features Stark battling well-known comic-book villain The Mandarin (Ben Kingsley). Gwyneth Paltrow returns as love interest Pepper Potts and Don Cheadle is back as Stark's best friend Col. James Rhodes, aka War Machine.

Will you see "Iron Man 3"? Tell us on Facebook.

Related content:

Source: http://entertainment.nbcnews.com/_news/2012/12/27/16191679-heres-your-holiday-card-from-iron-man?lite

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UFO-shaped gas station among this year's 'Preservation Wins'

It?s a travel itinerary as eclectic as they come: From a gas station shaped like a UFO, to an inn once proclaimed one of the most magnificent hotels in the country, to mystical rock pillars that fascinated an ancient culture. Put them all together and you have part of a collection that may make history buffs smile and explorers reach for their maps.

Source: http://video.msnbc.msn.com/hardball/50307185/

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Mass protests in India after a vicious gang rape of a female student help put a spotlight on countries that need to have more women police and judges. Antirape laws are not enough.

By the Monitor's Editorial Board / December 28, 2012

Indian police stand guard in front of a barricade as protesters march towards them during a Dec. 27 protest against a recent gang rape of a young woman in a moving bus in New Delhi. Prime Minister Manmohan Singh pledged to protect women while the young rape victim was flown to Singapore for treatment.

AP Photo

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On paper, women today have far more legal protections than 50 years ago. More than half of the world?s countries have written gender equality into their constitutions. But the brutal rape of a female student in India has thrown a global spotlight on the need to put legal norms for women into practice.

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For two weeks after the gang rape on Dec. 16, thousands of Indians have protested in New Delhi over the indifference of police and judges to the high number of incidents of rape. Legislators are now scrambling to pass antirape reforms. They have far to go.

India?s conviction rate in rape cases is no more than 26 percent. And that?s just for reported rapes. In a key measure of official insensitivity to violence against woman, only 7 percent of police officers are women. And a 1996 survey of judges in India found that 68 percent of them said provocative clothing is an invitation to rape.

One of the best ways to deter rape is to make it easier for women to report it, especially in a patriarchal and traditional society like India. Yet in a survey of 57 countries, only 1 in 10 women who say they experienced a sexual assault actually reported it.

Studies show that the reporting of sex crimes by women increases if female police officers are available to rape victims. The main reason is that it helps lessen the shame and stigma often felt by a female rape victim. And it allows for more comfort and consoling of the innocent.

Up and down the justice system more women are needed to deal with female-related crimes. Worldwide, only 9 percent of police and 27 percent of judges are women.

Many countries have become models of reform in how to deal with rape. Brazil set up women-only police stations in 1985, a practice now common in Latin America. Countries from Fiji to Pakistan provide special legal advice to women to help them through the courts. In parts of Africa, judges specializing in sex-crime cases travel to remote rural areas. In many countries, health workers are given special training in how to treat sexual-abuse victims.

According to a 2011 United Nations report on women, the justice system in most countries still needs to change its practices toward women. East Timor, for example, has only one doctor trained to collect evidence in rape cases.

?Although there is further to go, laws on violence against women are beginning to establish the kind of clear mandates and procedures that are needed to drive implementation and improve women?s access to justice,? stated the UN report.

The certainty of punishment for rape and the care that is given to rape victims will help curb rape. Equality for women means lifting their fears of rape through equality of treatment by law enforcement officials.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/EHJMgAlvM_s/India-gang-rape-why-women-are-needed-as-justice-officials

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NEW YORK (Reuters Health) - Seventh grade girls who have trouble reading are more likely to get pregnant in high school than average or above-average readers, according to a new study from Philadelphia.

Researchers found that pattern stuck even after they took into account the girls' race and poverty in their neighborhoods - both of which are tied to teen pregnancy rates.

"We certainly know that social disadvantages definitely play a part in teen pregnancy risk, and certainly poor educational achievement is one of those factors," said Dr. Krishna Upadhya, a reproductive health and teen pregnancy researcher from Johns Hopkins Children's Center in Baltimore.

Poor academic skills may play into how teens see their future economic opportunities and influence the risks they take - even if those aren't conscious decisions, explained Upadhya, who wasn't involved in the new research.

Dr. Ian Bennett from the University of Pennsylvania and his colleagues looked up standardized test reading scores for 12,339 seventh grade girls from 92 different Philadelphia public schools and tracked them over the next six years.

During that period, 1,616 of the teenagers had a baby, including 201 that gave birth two or three times.

Hispanic and African American girls were more likely than white girls to get pregnant. But education appeared to play a role, as well.

Among girls who scored below average on their reading tests, 21 percent went on to have a baby as a teenager. That compared to 12 percent who had average scores and five percent of girls who scored above average on the standardized tests.

Once race and poverty were taken into consideration, girls with below-average reading skills were two and a half times more likely to have a baby than average-scoring girls, according to findings published in the journal Contraception.

Birth rates among girls ages 15 through 19 were at a record low in the U.S. in 2011 at 31 births for every 1,000 girls, according to the Centers for Disease Control and Prevention. But that rate is still much higher in minority and poorer girls than in white, well-off ones, researchers noted.

And in general, it's significantly higher than teen birth rates in other wealthy nations.

Teen pregnancies are a concern because young moms and their babies have more health problems and pregnancy-related complications, and girls who get pregnant are at higher risk of dropping out of school.

Upadhya said the answer to preventing teen pregnancy in less-educated girls isn't simply to add more sex ed to the curriculum.

"This is really about adolescent health and development more broadly, so it's really important for us to make sure that kids are in schools and in quality educational programs and that they have opportunities to grow and develop academically and vocationally," she told Reuters Health.

"That is just as important in preventing teen pregnancy as making sure they know where to get condoms."

SOURCE: http://bit.ly/TcHB0s Contraception, online December 13, 2012.

Source: http://news.yahoo.com/poor-reading-skills-tied-risk-teen-pregnancy-153302656.html

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JOHANNESBURG (AP) ? Former South African President Nelson Mandela was released Wednesday from the hospital after being treated for a lung infection and having gallstones removed, a government spokesman said.

The 94-year-old anti-apartheid icon will continue to receive medical care at home.

Mandela had been in the hospital since Dec. 8. In recent days, officials have said he was improving and in good spirits, but doctors have taken extraordinary care with his health because of his age.

Mandela was released Wednesday evening and will receive "home-based high care" at his residence in the Johannesburg neighborhood of Houghton until he fully recovers, said presidential spokesman Mac Maharaj.

"We thank the public and the media for the good wishes and for according Madiba and the family the necessary privacy," said Maharaj in a statement, using Mandela's clan name, a term of affection. The statement requested that Mandela's privacy continue to be respected "in order to allow for the best possible conditions for full recovery."

David Phetoe, a resident of the Johannesburg township of Soweto, reacted with joy when he heard that Mandela was no longer in a hospital.

"It's not always the case, when people offer great expectations, that those expectations are fulfilled," he said. "In this case, we say in the same tone, in the Christmas mood and in the Christmas season, let him stick around for a while!"

Mandela is revered around the world as a symbol of sacrifice and reconciliation, his legacy forged in the fight against apartheid, the system of white minority rule that imprisoned him for 27 years.

The Nobel laureate served one five-year term as president after South Africa's first democratic elections in 1994. Although the country today struggles with poverty and inequality, Mandela is widely credited with helping to avert race-driven chaos as South Africa emerged from apartheid.

South African President Jacob Zuma was among those who joined Mandela's wife, Graca Machel, and other family members in wishing a Merry Christmas to Mandela at his hospital bedside in Pretoria, the South African capital.

"I think he is an icon of hope and we are very excited" that Mandela is out of the hospital, said Sipho Sibiko, a Soweto resident. "I personally know that he is one of the people that inspired me. He inspires a lot of people and we are excited that he has been released. We wish him many more joyous years and good health."

---

Thomas Phakane contributed to this report.

Source: http://news.yahoo.com/south-africa-mandela-released-hospital-192414250.html

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koijemala · Dec. 27, 2012

Dec. 27, 2012 ? One approach to understanding components in living organisms is to attempt to create them artificially, using principles of chemistry, engineering and genetics. A suite of powerful techniques -- collectively referred to as synthetic biology -- have been used to produce self-replicating molecules, artificial pathways in living systems and organisms bearing synthetic genomes.

In a new twist, John Chaput, a researcher at Arizona State University's Biodesign Institute and colleagues at the Department of Pharmacology, Midwestern University, Glendale, AZ have fabricated an artificial protein in the laboratory and examined the surprising ways living cells respond to it.

"If you take a protein that was created in a test tube and put it inside a cell, does it still function," Chaput asks. "Does the cell recognize it? Does the cell just chew it up and spit it out?" This unexplored area represents a new domain for synthetic biology and may ultimately lead to the development of novel therapeutic agents.

The research results, reported in the advanced online edition of the journal ACS Chemical Biology, describe a peculiar set of adaptations exhibited by Escherichia coli bacterial cells exposed to a synthetic protein, dubbed DX. Inside the cell, DX proteins bind with molecules of ATP, the energy source required by all biological entities.

"ATP is the energy currency of life," Chaput says. The phosphodiester bonds of ATP contain the energy necessary to drive reactions in living systems, giving up their stored energy when these bonds are chemically cleaved. The depletion of available intracellular ATP by DX binding disrupts normal metabolic activity in the cells, preventing them from dividing, (though they continue to grow).

After exposure to DX, the normally spherical E. coli bacteria develop into elongated filaments. Within the filamentous bacteria, dense intracellular lipid structures act to partition the cell at regular intervals along its length. These unusual structures, which the authors call endoliposomes, are an unprecedented phenomenon in such cells.

"Somewhere along the line of this filamentation, other processes begin to happen that we haven't fully understood at the genetic level, but we can see the results phenotypically," Chaput says. "These dense lipid structures are forming at very regular regions along the filamented cell and it looks like it could be a defense mechanism, allowing the cell to compartmentalize itself." This peculiar adaptation has never been observed in bacterial cells and appears unique for a single-celled organism.

Producing a synthetic protein like DX, which can mimic the elaborate folding characteristics of naturally occurring proteins and bind with a key metabolite like ATP is no easy task. As Chaput explains, a clever strategy known as mRNA display was used to produce, fine-tune and amplify synthetic proteins capable of binding ATP with high affinity and specificity, much as a naturally occurring ATP-binding protein would.

First, large libraries of random sequence peptides are formed from the four nucleic acids making up DNA, with each strand measuring around 80 nucleotides in length. These sequences are then transcribed into RNA with the help of an enzyme -- RNA polymerase. If a natural ribosome is then introduced, it attaches to the strand and reads the random sequence RNA as though it was a naturally-occurring RNA, generating a synthetic protein as it migrates along the strand. In this way, synthetic proteins based on random RNA sequences can be generated.

Exposing the batch of synthetic proteins to the target molecule and extracting those that bind can then select for ATP-binding proteins. But as Chaput explains, there's a problem: "The big question is how do you recover that genetic information? You can't reverse transcribe a protein back into DNA. You can't PCR amplify a protein. So we have to do all these molecular biology tricks."

The main trick involves an earlier step in the process. A molecular linker is chemically attached to the RNA templates, such that each RNA strand forms a bond with its newly translated protein. The mRNA-protein hybrids are exposed to selection targets (like ATP) over consecutive rounds of increasing stringency. After each round of selection, those library members that remain bound to the target are reverse-transcribed into cDNA (using their conveniently attached RNA messages), and then PCR amplified.

In the current study, E. coli cells exposed to DX transitioned into a filamentous form, which can occur naturally when such cells are subject to conditions of stress. The cells display low metabolic activity and limited cell division, presumably owing to their ATP-starved condition.

The study also examined the ability of E. coli to recover following DX exposure. The cells were found to enter a quiescent state known as viable but non-culturable (VBNC), meaning that they survived ATP sequestration and returned to their non-filamentous state after 48 hours, but lost their reproductive capacity. Further, this condition was difficult to reverse and seems to involve a fundamental reprogramming of the cell.

In an additional response to DX, the filamentous cells form previously undocumented structures, which the authors refer to as endoliposomes. These dense lipid concentrations, spanning the full width of the filamented E. coli, segment the cells into distinct compartments, giving the cells a stringbean-like appearance under the microscope.

The authors speculate that this adaptation may be an effort to maintain homeostasis in regions of the filamentous cell, which have essentially been walled off from the intrusion of ATP-depleting DX. They liken endoliposomes to the series of water-tight compartments found in submarines which are used to isolate damaged sections of the ship and speculate that DX-exposed cells are partitioning their genetic information into regions where it can be safely quarantined. Such self-compartmentalization is known to occur in some eukaryotic cells, but has not been previously observed in prokaryotes like E. coli.

The research indicates that there is still a great deal to learn about bacterial behavior and the repertoire of responses available when such cells encounter novel situations, such as an unfamiliar, synthetic protein. The study also notes that many infectious agents rely on a dormant state, (similar to the VBNC condition observed in the DX-exposed E. coli), to elude detection by antibiotics. A better understanding of the mechanisms driving this behavior could provide a new approach to targeting such pathogens.

The relative safety of E. coli as a model organism for study may provide a fruitful tool for more in-depth investigation of VBNC states in pathogenic organisms. Further, given ATP's central importance for living organisms, its suppression may provide another avenue for combating disease. One example would be an engineered bacteriophage capable of delivering DX genes to pathogenic organisms.

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Story Source:

The above story is reprinted from materials provided by Arizona State University. The original article was written by Richard Harth.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

Journal Reference:

Shaleen B. Korch, Joshua M. Stomel, Megan A. Le?n, Matt A. Hamada, Christine R. Stevenson, Brent W. Simpson, Sunil K. Gujulla, John C. Chaput. ATP Sequestration by a Synthetic ATP-Binding Protein Leads to Novel Phenotypic Changes inEscherichia coli. ACS Chemical Biology, 2012; : 121203123002005 DOI: 10.1021/cb3004786

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/HOgFMtBFq6s/121227143001.htm

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by: Iris0326

Economies all over the world are transforming into knowledge based economies. With the fundamentals of the world changing fast with the modifications in technology, it is important for a person to have specialization in a particular field in order to find a lucrative job.

Such type of specialization is imparted by vocational education training institutes. In the fields of health, technology, art and business administration, vocational education is generally imparted. The classification of these themes is further done into other specific courses.

Vocational educational training has earned increased renaissance of enthusiasm in today?s world of high demand for skilled workers for businesses. Vocational education in details is an exceptionally various and featured topic which involves analysis from a wide range of references and sources to several specified topics on training, occupational programs and career paths. You will find numerous sources online that may help in offering detailed data about such educational training. Due to the desperate need rising on a large scale amongst company houses for skilled workers, nowadays, all over the world people believe that trading schools are rebuilding their stable foundation.

The faculty of these Vocational education training institutes is highly experienced. They impart practical knowledge to their students. As a result the students are able to have a real life and practical industry experience. The students are also provided with internships.

There are various vocational education training located the world over. In fact every state has vocational institutes where the residents of the place can earn the degrees and become part of a specialized workforce. The majority of these training institutes work as per the rules and regulations of state education department. It is the education department of state or the central government that grants recognition to a training institute.

AVLC is a learning centre, which provides different kinds of training courses, such as vocational training, business training, corporate training, English IELTS and so on.
I am a Chinese girl. I like dogs very much.

http://www.avlc.org.au

This entry was posted in Management Training by . Bookmark the permalink.

Source: http://www.businessservicessupport.com/blog/2012/12/20/vocational-education-training-by-iris0326/

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Source: http://vince68.typepad.com/blog/2012/12/vocational-education-training-by-iris0326-small-business-training.html

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Griffith Prof. Donald Muldrow
(Fountainhead? Tanz Theatre/Black International Cinema Berlin/The Collegium - Forum & Television Program Berlin/Cultural Zephyr e.V.)

Fountainhead? Tanz Theatre is a production, performance and distribution unit, which was initiated and developed by Prof. Gayle McKinney Griffith and Prof. Donald Muldrow Griffith, both experienced artists from the U.S.A.
Fountainhead? engages people from various national, cultural, ethnic, socio-economic, religious backgrounds, and sexual identities, and works in a variety of artistic and cultural areas, with the goal of creating, experiencing and communicating intercultural exchange within its projects and to the world community.
Since its founding in 1980, Berlin/Germany, Fountainhead? has presented a variety of international, intercultural and interdisciplinary productions in the areas of dance, theatre, film festivals, television programming, film distribution, publications, seminars, exhibitions, workshops and musical presentations.
One of the productions is the annually presented Black International Cinema Berlin, which was founded by Fountainhead? in 1986 in Berlin/Germany and since then, has been produced and directed by Fountainhead? Tanz Theatre on a regular basis in Berlin/Germany, other European and US-American cities.
The festival screens cinema from the African Diaspora and other films from varied intercultural backgrounds or perspectives.

Black International Cinema Berlin originated from the Black Cultural Festival, which was produced and directed by Fountainhead? Tanz Theatre in 1986 for the first time in Europe, a 3-week event in Berlin, which presented the contributions of Black people to world culture through film, theater, dance, music, workshops and seminars, and was an homage to the legendary tap dancer, Carnell Lyons.
The venues were the Theatermanufaktur am Halleschen Ufer from March 3-16, music ? dance ? theatre; Hochschule der K?nste Berlin on March 11, symposium; Kino Arsenal from March 17-23, film.
Organization and Artistic Direction: Prof. Gayle McKinney Griffith (USA/Berlin), Prof. Donald Muldrow Griffith (USA/Berlin), Donald Muldrow McKinney Griffith II (USA/Berlin), Dr. Ntongela Masilela (South Africa);
in cooperation with: Prof. Dr. Abdul Alkalimat (USA), Uazuvara Ewald Katjivena (Namibia), Getinet Belay (Ethiopia), Joliba Africa Center; Organization: Erika Gregor (Arsenal Cinema, Germany); Organization Assistance: Annette Koschmieder (Germany)

Additionally, Fountainhead? produces and directs since the founding in 1995, the weekly intercultural television magazine program THE COLLEGIUM ? Forum & Television Program Berlin, broadcast Thursdays from 9-10 a.m. and Saturdays from 10-11 a.m. at Alex - Open Channel Berlin, and furthermore televised in Magdeburg, Wolfsburg, Dessau and additional cities.
In 1990 Fountainhead? Tanz Theatre established Cultural Zephyr e.V. as a not for profit organization, which administers the cultural and artistic undertakings of Fountainhead? Tanz Theatre.

Mottoes:
"I may not make it if I try, but I damn sure won?t if I don?t..."
Oscar Brown Jr.
"Mankind will either find a way or make one."
C.P. Snow
?Whatever you do..., be cool!"
Joseph Louis Turner
?Yes, I can...!?
Sammy Davis Jr.
?Yes, We can...!?
Barack Obama

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Germany

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Source: http://www.filmfestivals.com/blog/fountainhead/the_collegium_forum_television_program_berlin_kaveh_ghahremany_iran_filmmaker

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Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/273104572?client_source=feed&format=rss

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NYU biologists identify proteins vital to chromosome segregation

Public release date: 24-Dec-2012
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Contact: James Devitt
james.devitt@nyu.edu
212-998-6808
New York University

New York University biologists have identified how a vital protein is loaded by others into the centromere, the part of the chromosome that plays a significant role in cell division. Their findings shed new light on genome replication and may offer insights into the factors behind the production of abnormal numbers of chromosomes.

Their findings appear in the latest issue of the journal the Proceedings of the National Academy of Sciences.

The researchers focused on the organization and functioning of the centromere, which is responsible for chromosome segregationa process that ensures that replicating cells receive a complete copy of the genome. Disruption of this process can lead to the production of an abnormal number of chromosomesa condition evident in 90 percent of cancer cases.

To explore the mechanics of the centromere, the researchers examined fission yeast. This species of yeast is a model organism in cell biology because its chromosome replication and the regulation of its centromere are similar to that of humans.

In the PNAS study, the researchers focused on a protein, CENP-A, present in both humans and fission yeast. They specifically examined how it is incorporated into the centromere during cell division in order to better understand its role in this process.

Their results identified that a trio of proteinsDos1, Dos2, and Cdc20work together to assemble CENP-A at centromeres as they duplicate. They further observed that any disruption of this process subsequently places this vital protein outside of the centromerethereby preventing it from performing its role of ensuring proper chromosome segregation.

"CENP-A is the engineer of the centromere," explained Fei Li, an assistant professor in NYU's Department of Biology and the study's senior author. "Without this protein, the centromere simply can't function."

Li noted that many forms of cancer have been linked to malfunctioning CENP-A.

"Hopefully, these findings can contribute toward the development of improved strategies for the diagnosis and treatment of cancer," he added.

###

The study's other co-authors were: post-doctoral fellows Marlyn Gonzlez and Haijin He, Siyu Sun, an NYU graduate student, and Chen Li, who obtained her masters degree from NYU in 2012.

[ | E-mail | Share ]
?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

NYU biologists identify proteins vital to chromosome segregation Public release date: 24-Dec-2012
[ | E-mail | Share ]
Contact: James Devitt
james.devitt@nyu.edu
212-998-6808
New York University

New York University biologists have identified how a vital protein is loaded by others into the centromere, the part of the chromosome that plays a significant role in cell division. Their findings shed new light on genome replication and may offer insights into the factors behind the production of abnormal numbers of chromosomes.

Their findings appear in the latest issue of the journal the Proceedings of the National Academy of Sciences.

The researchers focused on the organization and functioning of the centromere, which is responsible for chromosome segregationa process that ensures that replicating cells receive a complete copy of the genome. Disruption of this process can lead to the production of an abnormal number of chromosomesa condition evident in 90 percent of cancer cases.

To explore the mechanics of the centromere, the researchers examined fission yeast. This species of yeast is a model organism in cell biology because its chromosome replication and the regulation of its centromere are similar to that of humans.

In the PNAS study, the researchers focused on a protein, CENP-A, present in both humans and fission yeast. They specifically examined how it is incorporated into the centromere during cell division in order to better understand its role in this process.

Their results identified that a trio of proteinsDos1, Dos2, and Cdc20work together to assemble CENP-A at centromeres as they duplicate. They further observed that any disruption of this process subsequently places this vital protein outside of the centromerethereby preventing it from performing its role of ensuring proper chromosome segregation.

"CENP-A is the engineer of the centromere," explained Fei Li, an assistant professor in NYU's Department of Biology and the study's senior author. "Without this protein, the centromere simply can't function."

Li noted that many forms of cancer have been linked to malfunctioning CENP-A.

"Hopefully, these findings can contribute toward the development of improved strategies for the diagnosis and treatment of cancer," he added.

###

The study's other co-authors were: post-doctoral fellows Marlyn Gonzlez and Haijin He, Siyu Sun, an NYU graduate student, and Chen Li, who obtained her masters degree from NYU in 2012.

[ | E-mail | Share ]
?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2012-12/nyu-nbi121912.php
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Getty Images

Lost in the reports and debates regarding Tim Tebow?s Wildcat tap out is the fact that the situation sparked the latest case of ESPN-on-ESPN crime.

Actually, it was more like an ESPN Battle Royal.

It started when Rich Cimini and Jane McManus of ESPNNewYork.com jointly reported on Sunday that Tebow asked to be omitted from the Wildcat package in Week 16 because the coaching staff had skipped over him when benching Mark Sanchez.? (You know, the same way the Broncos skipped over Brady Quinn when benching Kyle Orton in 2011.)

In an effort to control the damage, Tebow provided his version of the events to Adam Schefter of ESPN.? In exchange for the exclusive scoop, Schefter obviously had no choice but to pass along Tebow?s tale as he told it, without scrutiny or skepticism or cynicism.

And Tebow didn?t say that he had asked out of the Wildcat package, necessarily putting the spirit if not the letter of the two ESPN reports at odds.

But the conflict didn?t become obvious until Schefter, Merril Hoge, and Ron Jaworski appeared on the air to discuss the situation, via USAToday.com.? Schefter started by dutifully repeated what he had reported, without comment or opinion or editorial.

Enter Jaworski and Hoge, both of whom pressed Schefter for clarity as to the notion that Tebow told coach Rex Ryan that he didn?t want to play in the Wildcat package.? Schefter reiterated the guts of his report, skipping over the most important piece of information, apparently because either Schefter didn?t ask or Tebow didn?t tell.

?To me, it smells like three-day-old fish, OK?? Hoge said of Tebow?s story, which came only from Schefter?s report.? ?I think he?s phony as a three-dollar bill.? Because at the end of the day, what have I heard?? That he will do anything at any time.? You ask me to do it, I?ll do it.? And all of a sudden now that?s unacceptable?? That?s all of a sudden, ?Now I want to play quarterback or I?m not gonna play Wildcat?? . . . ? Tim Tebow, being the teammate he says he is, accepts that.? Because he says I?ll do anything for the team.? That?s all I?ve ever heard about him.? Well I think this sound shows really what he?s about.?

Jaworski then tried to suggest that Tebow never said he wouldn?t play Wildcat quarterback, citing derisively (and with air quotes) that it?s merely been ?reported? via ?sources.?? And in so doing, jumping off the top rope and landing on the work of Cimini and McManus.

Enter Schefter, who then explained that it was a ?culmination of a full season of frustration and disappointment,? and that ?somehow it?s morphed into ?I?m taking myself out.??

Hoge then made an observation that Schefter and Jaworski arguably ignored when subtly pile-driving the reporting of their colleagues, Cimini and McManus.? ?If you are for the team and that is what you do care about,? Hoge said, ?then guess what?? Whatever that coach makes, that decision, sure you can be upset, but you still do what you can for the team.? You don?t make a rift, you don?t sit there and argue.?

Next, Jaworski revisited the question of whether Tebow said what Cimini and McManus claim he said.? ?I want Tim Tebow, if this was said, to say on Tuesday, ?I told Rex Ryan I don?t want to take the Wildcat snaps,?? Jaworski said.? ?We?ve got a lot of hearsay here.?

And in that one swing, Jaworski again questioned the veracity of his colleagues? original report and indirectly chided Schefter for not asking the obvious follow-up questions when talking to Tebow.

Either way, it should be no surprise that the implosion of Tebow?s 2012 season created chaos at the network that was devoted to covering it.

Source: http://profootballtalk.nbcsports.com/2012/12/25/mike-mccarthy-hopeful-injured-packers-can-return-this-week/related/

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By Reuters

BERLIN - A 65-year-old man thought to be sleeping while sitting upright on a Berlin underground train as it crisscrossed the German capital was actually dead, police said on Sunday.

"It's tragic," a Berlin police spokeswoman said. "We don't know how long he was sitting dead on the train nor do we know the exact cause of death yet. There are no indications of foul play. He seems to have died of natural causes."

The man was found in the U-8 underground train line that runs all night at the Weinmeisterstrasse station at 5:45 a.m. when a rail worker tried wake the man up by gently shaking him. Medics were called in but could only pronounce the man dead.

A preliminary investigation showed no indications of the man being murdered. A more detailed autopsy is planned for Monday.?

More world stories from NBC News:

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Source: http://worldnews.nbcnews.com/_news/2012/12/23/16105169-dead-passenger-found-riding-berlin-subway?lite

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Residence near shooting and fire in Webster evacuated. (Max Schulte/Rochester Democrat&Chronicle via Twitter)

A gunman set a trap and shot and killed two firefighters responding to an early morning blaze in Webster, N.Y., police officials said. Two other firefighters were also shot and are both listed in guarded condition at a local hospital.

"It does appear that it was a trap that was set for first responders, but the cause or reasons we don't have at this time," said Webster Police Chief Gerald Pickering as he described? the scene where shots were fired at West Webster firefighters when they arrived at 5:35 a.m. to battle the blaze along Lake Road. Webster is about 10 miles east of Rochester.

The apparent gunman was found dead at the scene, but it?s unclear if he was killed by? a self-inflicted gunshot or if it was from a weapon from police officers who were chasing him.

The victims were Mike Chiapperini, also a lieutenant and public information officer with the local police department, and Tomasz Kaczowka, Pickering said.

Chiapperini was described by Pickering as a lifelong firefighter who started with the department's explorer program and had about 20 years of experience. Kaczowka was a younger firefighter and was also a 911 dispatcher, he said.

West Webster firefighters Joseph Hofsetter and Theodore Scardino were seriously injured and are at Strong Memorial Hospital with gunshot wounds, a hospital spokeswoman said.? Scardino? has? injuries to his chest and lungs. Hofsetter was injured in the pelvis, the spokeswoman said at a media briefing.

An off-duty police officer from nearby Greece, N.Y.? John Ritter was also injured by shrapnel during the shooting, Pickering said.

Pickering said that one of the firefighters who survived made his way across a bridge to get to safety. The other three did not make it across, Pickering said. Police arrived and rescued the other three firefighters, but two were fatally shot, Pickering said.

"These are volunteers who get up in the middle of the night to fight fires. They don't expect to be shot and killed," a tearful Pickering said at the press conference.

The morning scene was described as chaotic as police and firefighters dealt with an immense blaze as well as gunshots,? local news station WHAM-TV? reports.

?I?m not aware of anything like this happening in Webster, obviously not a firefighter being fired upon,? Webster Fire Marshal Rob Boutillier told the Democrat and Chronicle.? Pickering described Webster as resort lakeside community that is quiet and usually peaceful.

There at least four houses that have been damaged by the fire along Lake Road, WHAM-TV reported. Firefighters had to leave the scene and stop battling the blazes while police secured the scene. They continue to battle the blaze.

Source: http://news.yahoo.com/blogs/lookout/two-firefighters-shot-killed-while-responding-webster-n-163105823.html

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